Experience


Posit PBC (formerly RStudio Inc.)

Engineering:

  • Principal Software Engineer (2023 - present)
  • Software Engineer (2016 - 2023)

Responsibilities:

  • Develop software for statistical modeling, visualization, and analysis for data science.

Pfizer Global R&D

Nonclinical Statistics:

  • Senior Director (2015 - 2016)
  • Director (2009 - 2015)
  • Associate Director (2005 - 2009)

Responsibilities:

  • Apply predictive modeling to diverse areas such as patient analytics, chemistry, manufacturing, etc.

  • Manage a group of statisticians supporting systems biology in drug discovery

  • Support drug discovery programs, including

    • Project support for specific development programs
    • in-silico/systems biology: microarray, PCR, and RNA interference experiments, mechanistic modeling
    • Computational and medicinal chemistry
    • Drug safety (target-based and compound screening)
    • Biomarker discovery and modeling
    • Assay characterization and validation
    • Scientific computing

  • Design, implement, and support statistical computing, including several R packages; maintain platforms for gene expression and QSAR modeling; develop parallel processing algorithms and other tools.

  • Teach internal courses on computing, statistical analysis of gene expression experiments, and predictive modeling.

Becton-Dickinson (BD) Diagnostic Systems

Statistics:

  • Manger (2002 - 2005)
  • Senior Statistician (1998 - 2002)

Responsibilities:

  • Designed, implemented, and maintained predictive algorithms for instrumented systems.
  • Managed departmental resource planning and budget for clinical and nonclinical statistics.
  • Coordinated the work activities of 9 - 15 direct reports (including statisticians, programmers, database analysts, and software testers).
  • Designed and supported data analysis methodologies for molecular biomarker discovery.
  • Supported product development for diagnostic products and cell culture services.
  • Provided oversight to clinical protocol design and software development.
  • Developed statistical aspects of Six Sigma programs for manufacturing and product development.